|Life is beautiful again. Indication: Idiopathic Parkinsonism. Special instructions: PRECAUTIONS: All known precautions and contraindications as applicable to synthetic L-dopa formulation should also be followed while prescribing Zandopa. Monoamine oxidase inhibitors, if taken by patients, must be discontinued atleast 2 weeks prior to institution of Zandopa therapy. As with levodopa,periodic evaluations of hepatic, haematopoietic, cardiovascular and renal functions are recommended during extended therapy with zandopa Zandopa should be administered with caution in severe cardiovascular or pulmonary disease, bronchial asthma, renal, hepatic, or endocrine disease and in presence of peptic ulcer or chronic narrow angle glaucoma. SIDE EFFECTS: Side effects include nausea, anorexia, cardiac irregularities, orthostatic hypotension, weight gain, hot flushes, numerous dyskinesias and psychiatric symptoms such as agitations, hallucinations, delusions and nightmares. Side effects as encountered with synthetic L-dopa formulations have not been seen to the same severity with Zandopa.